#1 Best Value of 24 Mexico Casino Hotels ; 2. Seadust Cancun Family Resort · 6, reviews. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Excite. The Pyramid Cancun · 4, reviews. Unwind. Upcoming Events. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. A warm and friendly environment with slot machines at the Main Casino. These casinos and gaming sites are owned by 14 New Mexico. Must be 21+. Colorful bingo cards and round bingo balls w/numbers. 1. . Indulge. Saturdays in. Sky City Casino is open 24 hours daily. No Smoking Facility. Win. With three live entertainment venues, you'll find something around every corner. Swirls of Cash. Our New Mexico casino is open 24/7 daily. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. at Isleta Resort & Casino. Learn More. It's a warm, friendly environment with slot machines. #2 Best Value of 24 Mexico. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Open 24 hours, 7 days a week! What's happening. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. The Travel center includes a casino area with 45 slot machines.